Toxic Interfaces of Neurones, Smoke and Genes

InhaltsangabeNeural Membranes as a Target of Toxicity.- Nerve Membrane Ionic Channels as the Target of Toxicants.- Neurochemical Effects of DDT in Rat Brain In Vivo.- The Pharmacology of Simple Molecules.- Membrane Lipid Changes in Organic Solvent Tolerant Neural Cells.- Effects of Methylglyoxal on Central and Peripheral Cholinergic Responses.- Effects of Diazepam, Tofizopam or Phenytoin During Foetal Development on Subsequent Behaviour and Benzodiazepine Receptor Characteristics in Rats.- The Effect of Ethanol on the Release of Free Fatty Acids from the Brain In Vivo; A study with a Push-Pull Cannula.- Aspects of Smoke Toxicology.- Review of Epidemiology in Relation to Passive Smoking.- Aerosols of Smoke, Respiratory Physiology and Deposition.- Monitoring Absorption by Means of Determination of Nicotine and Cotinine.- Monitoring Urine for Inhaled Cannabinoids.- Microcomputer Assisted Measurement of Inhalation Parameters During Smoking.- No Difference Between Urinary Mutagenicity in Smokers of Low-Tar and Medium-Tar Cigarettes: A Double Blind Cross-Over Study.- Cigarette Smoking, Serum Lipids and Angiographically Assessed Coronary Artery Disease.- Genetic Influences on Toxicity.- The Case for Isogenic strains in Toxicological Screening.- Polymorphism in Drug Metabolism - Implications for Drug Toxicity.- Inter-Individual Variations in Carcinogen Metabolism.- Interethnic Differences in the Detoxification of Organophosphates: The Human Serum Paraoxonase Polymorphism.- DNA-Mediated Restoration of Aryl Hydrocarbon Hydroxylase Induction in a Mouse Hepatoma Mutant Defective in Nuclear Translocation of the Ah Receptor.- Species Differences in the Covalent Binding of p-Chloro-o-Toluidine to DNA.- Effects of Peroxisome Proliferators In Vivo and in Primary Hepatocyte Cultures from Chinese and Syrian Hamsters.- Cardiovascular Toxicity.- Cardiotoxicity Mechanisms from the Point of View of Preclinical or Premarketing Safety Evaluation.- Detection of Cardiotoxic Hazards.- Interaction of Calcium Antagonists with ?-Adrenoceptor Blocking Agents.- Cardiotoxicity of Digitalis.- Cardiotoxic Actions of Doxepin and Barium Chloride in Conscious Rabbits.- Dose Dependence of the Nifedipine/Digoxin Interaction?.- Experimental Compound OR-K-242-HCL, an Anilide Derivative Slows Conduction Velocity of the Heart in the Conscious Beagle Dog.- Nifedipine Induces Intense Nausea and Vomiting in Young Healthy Volunteers.- The Effect of a Novel Inotropic/Vasodilating Compound on the Dog Heart at Toxicological Doses.- Routine Toxicity Testing: Problems and Solutions.- Toxicology - The Next Decade.- Application, Limitations and Research Requirements of In Vitro Test Systems in Toxicology.- The Questionable Value of Long-Term Animal Toxicity Studies: A Regulatory Dilemma.- To what Extent can Results of Experimental Studies be Extrapolated in Predicting Adverse Side Effects of Drugs in Man.- Validity of Toxicity Documents of Pesticides and Good Laboratory Practice.- Carcinogenicity Testing in Nude Mouse Cell Cultures.- Pharmacokinetically Governed Design of Animal Toxicity Studies of a New Antidepressant Drug.- Dog and Swine as Models for Testing Indomethacin Induced Gastrointestinal Irritation.- A Rapid Method for Quantitation of Toxic Heart Dilation in Rats.- On the Usefulness of Minipigs in Toxicological Testing of Pesticides.- Cellular Mechanisms of Toxicity.- Cellular Defense Mechanisms against Toxic Substances.- Differences in the Induction of Autoimmune Responses in A. SW/SnJ Mice by Various Agents.- Morphological Alterations induced by Patulin on Cultured Hepatoma Cells.- The Effects of Estrogen and Antiestrogens on Light-Induced Retinal Damage in Rat.- Reaction Products of Styrene Oxide with Deoxynucleosides and DNA In Vitro.- Binding of Styrene Oxide to Amino Acids, Human Serum Proteins and Hemoglobin.- Cytogenetic Effects of a Novel Antiestrogen Toremifene FC-1157a: A Comparison with Diethylstilbestrol and Tamoxifen.- Toxicity of Richterite in Hemolysis Test and Macrop